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Stevie Wilkerson hit his first major league homer, John Means pitched five effective innings on his birthday and the Baltimore Orioles beat the Chicago White Sox 4-3 Wednesday night to secure their second winning streak of the season.

Baltimore won two of three to capture its first series since April 1-3 in Toronto. The two straight victories are the Orioles' most since a four-game run that began at Yankee Stadium on March 30.

Wilkerson's second-chance solo shot off Ervin Santana (0-2) put the Orioles up 4-1 in the fourth. Earlier in the at-bat, Wilkerson walked to first base after apparently being hit by a pitch, but a replay proved otherwise. Three pitches later, he capped his 53rd big league at-bat by sending a hanging slider into the center-field bleachers.

Making his third major league start, Means (3-2) marked his 26th birthday with a career-high six strikeouts. The lefty allowed one run and four hits.

Mychal Givens worked the final two innings for his first save. After allowing an RBI double to José Abreu in the ninth, Givens threw a wild pitch. The right-hander then got Yoan Moncada to hit a two-out grounder to shortstop Richie Martin, who made a nice grab moving to his left before throwing to first.

Martin had entered as a defensive replacement in the top of the inning.

Still trying to regain the form that enabled him to win 16 games for Minnesota in 2017, Santana gave up four runs in 4 2/3 innings. The 36-year-old has a 9.45 ERA in three starts with Chicago after going winless last year during an injury-riddled season with the Twins.

The Orioles went up 2-0 in the first when Dwight Smith Jr. and Renato Núñez hit successive two-out doubles and Rio Ruiz delivered an RBI single.

Down 4-1, the White Sox got a run in the sixth and threatened for more. After Baltimore reliever Evan Phillips hit Ryan Cordell with a pitch to force in a run, Jose Rondon struck out and Paul Fry came in to retire pinch-hitter Nicky Delmonico on a grounder.

WRIGHT MOVE

The Orioles obtained minor league infielder Ryne Ogren from Seattle for right-hander Mike Wright, who was designated for assignment by Baltimore on Sunday.

Wright was 0-1 with a 9.45 ERA this year and 10-12 lifetime over five seasons.

"We were pulling for him to have success here, and now he's getting an opportunity with another big league club," manager Brandon Hyde said. "Happy for him. Seattle is getting a really good person."

Ogren, 22, was drafted in the 12th round by the Mariners in 2018. The Orioles assigned him to Class A Delmarva.

TRAINER'S ROOM

White Sox: Starter Lucas Giolito (hamstring) will throw from the mound on Friday. Manager Rick Renteria was encouraged by the right-hander's progress, saying, "As long as he's doing well and we're comfortable, he'll be back sometime soon." ... John Jay (groin) took batting practice and was throwing on Wednesday, but there is no timetable for his return.

Orioles: RHP Nate Karns (forearm tightness) will make a rehab appearance Thursday with Class AA Bowie.

UP NEXT

White Sox: After taking Thursday off, Chicago starts Carlos Rodón (3-2, 2.89 ERA) in the opener of a three-game series against the visiting Detroit Tigers.

Orioles: Following an off day Thursday, Baltimore begins a three-game series in Minnesota on Friday night. The Orioles haven't defeated the Twins since the 2018 season opener.

Ozzie Albies homered on the game's first pitch and Ronald Acuna Jr. scored from first base on Yasiel Puig's fifth-inning error, helping the Atlanta Braves to a 3-1 win over the Cincinnati Reds on Wednesday night.

Acuna scored easily when Puig misplayed Nick Markakis's line drive single to right, allowing it to skip under his glove and roll to the wall for a two-base error.

Josh Donaldson doubled down the left field line to drive in Albies with an insurance run in the ninth.

Mike Soroka (1-1), in his second start of the season and seventh of his career, tied his career high with seven strikeouts while allowing five hits and one run with three walks in 5 2-3 innings.

The Reds loaded the bases with two outs in the sixth against Soroka, but reliever Josh Tomlin got slumping pinch-hitter Scott Schebler to ground out to first baseman Freddie Freeman. Schebler has two hits in his last 27 at bats and is batting .150 this season.

Luke Jackson and Dan Winkler combined to face the minimum six batters over the next two innings before A.J. Minter pitched a perfect ninth for his third save.

Albies smashed Tanner Roark's 91-mph four-seam fastball over the Reds bullpen down the right field line for his third home run of the season. The leadoff homer was his first of the season and fifth of his career.

The Reds quickly rallied in the bottom of the first on Joey Votto's leadoff walk, his fourth consecutive walk over two games, and back-to-back singles by Eugenio Suarez and Jesse Winker.

The Braves put at least two runners on base in each of the next three innings, but couldn't push them across the plate, stranding seven through four innings.

Roark (1-1) got through five innings, allowing six hits and two runs with three walks and four strikeouts. He also hit a batter.

TRAINER'S ROOM

Braves: LHP Jonny Venters threw a bullpen before Wednesday's game and could be ready for a rehab assignment, manager Brian Snitker said. Venters went on the IL on April 15 with a right calf strain.

Reds: IF Scooter Gennett hopes in the next week to firm up a timetable for a rehab assignment. Gennett has missed the entire season with a strained right groin.

UP NEXT

Braves: RHP Julio Teheran (2-2, 5.61) allowed 11 hits and seven runs in five innings in his last start against Cincinnati and got the decision in a 13-8 Atlanta win on June 4, 2017.

Reds: RHP Jose Castillo (2-1, 1.47) was switched from starting Friday in St. Louis to starting this game. The Braves have hit a combined .294 over eight innings in two games against Castillo.

One St. Louis Cardinals pitcher reached a career milestone, while another added to his growing reputation as one of the league's toughest relievers.

Adam Wainwright was warm enough on a cool day, allowing one run in six innings for his 150th career victory as Cardinals beat the Milwaukee Brewers 5-2 on Wednesday to complete a three-game sweep.

"It means something to me," Wainwright said. "I'm proud to have been a Cardinal for the whole time of it, too, and I'm proud to win most of those with my brother (catcher) Yadier Molina and a lot of those in front of these great fans in St. Louis."

Jordan Hicks preserved the win with a strikeout of last year's MVP, Christian Yelich, who had most of the day off but still got a chance to rescue the Brewers. Yelich came up as a pinch-hitter with the bases loaded in the ninth inning.

Hicks, known for his 100-mph-plus fastball, only threw one heater out of his five pitches to Yelich, the only batter he faced. He got the strikeout on a 91-mph changeup, earning his seventh save in eight chances.

"I won't tell you our scouting report, but obviously we're facing a good hitter," Molina said. "He's hot and you've got to be smart in that situation."

The Brewers loaded the bases with two out while trailing 5-1, but manager Craig Counsell elected to stick with Ben Gamel instead of going to Yelich sooner. Andrew Miller walked Gamel, setting up the Yelich-Hicks matchup.

"If you put him (Yelich) up in a tying situation, I felt like we were just counting on a home run there, and then Hicks has got some good matchups," Counsell said. "So this way I thought that one of our other guys had to do the job, and Ben Gamel did the job, and I thought that gave us a real legitimate shot."

Wainwright (2-2) matched his season low in runs allowed, and it was his first quality start in a game with a starting temperature of 60 degrees or cooler since May 27, 2017.

"Let's just step back and appreciate what an accomplishment that is," Cardinals manager Mike Shildt said of Wainwright's 150th win. "You look at the Mount Rushmore of the pitchers in this organization, which is pretty impressive, he's carving out a spot."

Marcell Ozuna and Molina homered for the Cardinals as part of a four-run fourth. Ozuna's three-run homer extended his on-base streak to 14 games, and it was his 17th career homer against the Brewers, the most he's had against any opponent.

Molina's blast extended his 12-game hitting streak, tying him with Paul DeJong for the longest by a Cardinal this season. Paul Goldschmidt got the rally started with a single, extending his hitting streak to 11 games.

St. Louis' three-game sweep of Milwaukee was its first against its NL Central rival since July 1-3, 2016. The teams have already played 10 times this season, and Wednesday's result evened the season series at 5-5. They combined for 45 home runs in the 10 games.

Jhoulys Chacin (2-3) lasted four innings, allowing four runs on five hits. Zach Davies on April 13 was the last Brewers pitcher to turn in a quality start.

Brewers starters have gone 8-7 with a 5.84 ERA this season, and they are the only team in the NL whose starters average less than five innings per game. Help is coming soon, however, in the form of left-hander Gio González, who has agreed to a one-year contract with Milwaukee, a person familiar with the negotiations told The Associated Press. The person spoke to the AP on condition of anonymity Wednesday because the agreement had not been announced.

"He pitched good for us last year," Chacin said of Gonzalez. "Wherever he can help us to get going, because I think outside of having to get going, we haven't pitched deep in games. We haven't put the team in a good position to win ballgames every day."

Eric Thames homered in the first for Milwaukee. The team's last 23 runs have come via the home run.

BADER'S BACK

Before the game, the Cardinals activated OF Harrison Bader (right hamstring strain) from the 10-day injured list and optioned RHP Daniel Ponce de Leon to Triple-A Memphis.

TRAINER'S ROOM

Brewers: Yelich (rest) wasn't in the starting lineup for the first time this season.

Cardinals: OF Tyler O'Neill (right elbow ulnar nerve sublaxion) went 0 for 3 with two strikeouts in his first rehab game at Double-A Springfield on Tuesday night.

UP NEXT

Brewers: RHP Chase Anderson (2-0, 3.00 ERA) will get the start as Milwaukee continues its trip against the Mets on Friday. Anderson is 2-2 with a 3.94 ERA in six career starts against the Mets.

Cardinals: RHP Miles Mikolas (2-1, 4.97) kicks off a three-game set against the visiting Reds and RHP Anthony DeSclafani (0-1, 5.59) on Friday. Mikolas gave up a pair of runs in eight innings on Saturday, becoming the first St. Louis starter this season to record an out beyond the sixth inning.

Marshall County High School named Laura Kinder as the new head volleyball coach on Wednesday.

Kinder is a graduate of Harrisburg (IL) High School where she was a 4-year varsity volleyball player. She is a 2012 graduate of Southern Illinois University at Edwardsville.

Kinder has three years prior coaching experience at Henderson County High School where she served on the volleyball staff and was head coach of the middle school program while at Henderson County.

Kinder has been an English teacher at Marshall County High School since 2015.

“I am excited for the opportunity to work with the girls and the Marshall County volleyball program,” Kinder said. “I’m ready to work hard and be competitive in our region.”

Paul DeJong wanted another chance against Milwaukee reliever Alex Wilson. He made the most of it.

DeJong hit a tiebreaking, leadoff homer in the eighth inning, Yadier Molina had three hits and two RBIs, and the St. Louis Cardinals beat the Milwaukee Brewers 4-3 Tuesday night.

DeJong took Wilson (1-1) deep on a 2-2 slider to make it 3-2.

"I knew he has a lot of stuff that goes away, a little slider, a little cutter and I wasn't looking to pull him," DeJong said. "I just went with the slider away. I rolled over a slider last night. I knew I wanted to see him deeper in the count, and I just got off a good swing off."

The Cardinals have won four in a row. The Brewers have lost five of six.

Milwaukee had three solo homers, two by Travis Shaw and another by Orlando Arcia. The Brewers had four solo homers in a 13-5 loss Monday. All Milwaukee's runs in this series have come from home runs.

Molina hit his second double with one out in the eighth, scoring Jose Martinez, who had walked to go with two singles. Molina stole third but was stranded there. It was his first stolen base this season and the 17th time he's stolen third in his career.

"We're doing a pretty good job being aggressive and taking extra bases," Molina said. "That's what part of our game is right now, we're going to take advantage of what they give us."

Andrew Miller (1-1) struck out two in a perfect eighth to pick up his first win as a Cardinal. Miller's last victory was on Aug. 9 against Minnesota, and the two-time All-Star has a disappointing 6.23 ERA this season.

"That was Andrew Miller tonight," Cardinals manager Mike Shildt said. "He had a really filthy slider. It's a pitch that's hard to contend with. With his fastball, that's pretty lethal combination."

Jordan Hicks pitched the ninth for his sixth save. Shaw led off the ninth with his second home run. After a walk, Hicks got a strikeout and a double play.

"We put together a decent ninth against Hicks," Milwaukee manager Craig Counsell said. "It just wasn't enough."

Paul Goldschmidt singled home Matt Carpenter with two outs in the fifth, giving St. Louis a 2-1 lead. Carpenter drew a walk and then stole second, his first this season, to get into scoring position.

Arcia belted a homer to center to lead off the fifth and tie it at 1. Shaw's homer off reliever John Gant tied it at 2 in the sixth. Shaw also homered in Monday's series opener when he snapped an 0-for-17 skid.

"We're playing good teams," Shaw said. "We need to keep our head above water and hopefully finish out this trip well."

St. Louis starter Daniel Ponce de Leon, who was activated before the game, started in place of the injured Michael Wacha. In his season debut, Ponce de Leon pitched five innings, striking out seven and allowing two hits and one run.

Milwaukee starter Zach Davies pitched 4 2/3 innings. He gave up seven hits and two runs.

CARLOS MARTINEZ UPDATE

Cardinals RHP Carlos Martinez, out with right shoulder cuff strain, has missed 23 games. He threw a side session Tuesday. He's up to 30 pitches of moderate-to-high intensity. He will throw again Friday and likely one more session after that, Shildt said. When he comes back, it will be as a reliever.

ROSTER MOVES

Cardinals: INF/OF Drew Robinson, who was recalled from Triple-A Memphis on Monday, was sent back down Tuesday to make room for Ponce de Leon.

TRAINER'S ROOM

Brewers: RHP Freddy Peralta (right shoulder inflammation) will throw a full bullpen session Wednesday. His 15-pitch light bullpen Monday went fine, the Brewers said. He could rejoin the rotation in the next homestand, which begins Monday against Colorado.

Cardinals: OF Harrison Bader (right hamstring strain) ran the bases before the game. He is expected to be activated from the injured list before Wednesday's game. ... OF Tyler O'Neill (right ulnar nerve subluxation) was set to begin his rehab assignment Tuesday night in Double-A Springfield. He will play three games there and get four at-bats in each. ... RHP Luke Gregerson (right shoulder impingement) visited with team doctors Tuesday and will returning to Doube-A Springfield. He will be used out of the bullpen as a regular reliever instead of structured work.

UP NEXT

Brewers: Jhoulys Chacin (2-2, 5.92) will be making his second start this season against St. Louis.

Cardinals: Adam Wainwright (1-2, 4.74) pitched a season-high seven innings in his last start (April 11) against the Brewers.